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The Heartbreaking Health Battles of 10 Beloved Stars in 2026

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Christina Applegate

Christina Applegate
Christina Applegate

The Diagnosis: Multiple Sclerosis (MS)

Best known for her comedic timing in Married… with Children and Dead to Me, Christina Applegate revealed her Multiple Sclerosis diagnosis while filming the final season of her hit show. MS is an unpredictable disease of the central nervous system that disrupts the flow of information within the brain.

Since then, she has been candid about her need for walking aids and the exhaustion that comes with the chronic illness. Her journey highlights the importance of early diagnosis and the high costs associated with managing autoimmune conditions in the United States.


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